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Shao HF, He Y, Fu JZ (2018) Research advance of degradable artificial bone with additive manufacturing: customization from geometric shape to property. Jin JC, Wang Y, Ma WH, Zhu YB (2016) Application progresses of 3D-bioprinting technology in scaffold constitution for tissue engineering and tissue regeneration. J Biomed Mater Res B Appl Biomater 89:325–334Ĭampoli G, Borlefs M, Amin Yavari S, Wauthle R, Weinans H, Zadpoor AA (2013) Mechanical properties of open-cell metallic biomaterials manufactured using additive manufacturing. Mullen L, Stamp RC, Brooks WK, Jones E, Sutclife CJ (2009) Selective laser melting: a regular unit cell approach for the manufacture of porous, titanium, bone in-growth constructs, suitable for orthopedic applications. Heinl P, Müller L, Körner C, Singer RF, Müller FA (2008) Cellular Ti-6Al-4Vstructures with interconnected macro porosity for bone implants fabricated by selective electron beam melting. J Clin Rehabil Tissue Eng Res 17(3):509–516 Gui H, Li P, Zhang W (2013) Materials and methods for preparation of tissue-engineered cartilage Scaffolds. Han N, Zhao J (2010) The development of scaffolds in cartilage tissue engineering. Surmeneva M, Surmenev R, Chudinova E, Koptioug A, Tkachev M, Gorodzha LE (2017) Fabrication of multiple-layered gradient cellular metal scaffold via electron beam melting for segmental bone reconstruction. Liang JH, Li RY, Liu GC et al (2017) Design of the porous orthopedic implants: research and application status. The processing path was obtained directly from the voxel model, thus providing a feasible method for the design and manufacture of the porous bone scaffold. The parameters including pore size and porosity on the bone scaffold could be controlled through adjusting the voxel size and pore unit structures. It can be concluded from the experiment that the porous bone scaffold could be constructed by the proposed algorithm.
Then, an isometric scanning line of cross-sectional profile was filled and dispersed to construct voxel model subsequently, the pore unit was designed based on voxel, and the voxel model of porous bone scaffold was constructed by filling the pore units finally, combined with additive manufacturing process, a method to generate processing path directly based on the voxel model was proposed. Secondly, a rapidly slicing algorithm based on surface model was proposed to obtain the cross-sectional profile of bone scaffold. Firstly, the surface of model triangular facets of bone scaffold was reconstructed by moving cube (MC) algorithm with the computer tomographic (CT) images. For solving the modeling problem of porous structure design of bone scaffold, a modeling method of porous bone scaffold based on voxel model was proposed.